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Complete Information on Castleman’s disease

POSTED BY admin on Jun 6, 2008 under Health

Castleman’s disease is an uncommon lymphoproliferative disorder. It is characterized by non-cancerous (benign) growths (tumors) that may develop in the lymph node tissue throughout the body.

It involves hyperproliferation of certain B cells that often produce cytokines. There are several variants of Castleman’s disease. Unicentric Castleman’s disease involves tissue growths at only a single site; Multicentric Castleman’s disease (MCD) involves growths at multiple sites. Castleman disease affects both males and females, and may occur at any age, but typically it does not affect children.

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