Complete Information on Caroli disease
Caroli disease also is known as communicating cavernous ectasia. Caroli’s disease is a rare inherited disorder of the liver. It is characterized by saccular and cystic dilatation of intra-hepatic biliary ducts.
Caroli disease is associated with recurrent bacterial cholangitis and stone formation. It is distinct from other diseases that cause ductal dilatation caused by obstruction. It is not one of the many choledochal cyst derivatives. It may be associated with autosomal-recessive polycystic kidney disease. The likely mechanism involves an in utero event that arrests ductal plate remodeling at the level of the larger intrahepatic bile ducts.
Complete Information on Boerhaave syndrome
Boerhaave syndrome is a rare spontaneous rupture to the esophagus. Esophagus most commonly results from a sudden increase in intraesophageal pressure combined with negative intrathoracic pressure caused by straining or vomiting.
In most cases of Boerhaave’s syndrome, the tear occurs at the left posterolateral aspect of the distal esophagus and extends for several centimeters. The condition is associated with high morbidity and is fatal in the absence of therapy. The occasionally nonspecific nature of the symptoms may contribute to a delay in diagnosis and a poor outcome.
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