Complete Information on Blood coagulation disorders
Coagulation is initiated almost instantly after an injury to the blood vessel damages the endothelium.
Blood coagulation is part of an important host defense mechanism termed hemostasis. Upon vessel injury, platelets adhere to macromolecules in the subendothelial tissues and then aggregate to form the primary hemostatic plug. Coagulation is highly conserved throughout biology; in all mammals, coagulation involves both a cellular (platelet) and a protein (coagulation factor) component. The platelets stimulate local activation of plasma coagulation factors, leading to generation of a fibrin clot that reinforces the platelet aggregate.
Complete Information on Diabetes mellitus with Treatment and Prevention
People with diabetes often develop bacterial and fungal infections, typically of the skin. When the levels of sugar in the blood are high, white blood cells cannot effectively fight infections.
Diabetes mellitus is the blood sugar level is high is unusual chaotic because the body does not produce the enough insulin. Normally, blood glucose levels are tightly controlled by insulin, a hormone produced by the pancreas. Insulin lowers the blood glucose level. When the blood glucose elevates, insulin is released from the pancreas to normalize the glucose level. In patients with diabetes, the absence or insufficient production of insulin causes hyperglycemia. Diabetes is the most significant cause of adult blindness in the non-elderly, the leading cause of non-traumatic amputation in adults, and diabetic nephropathy is the main illness requiring renal dialysis in the united states. Therefore deficiency of insulin or the insensitivity of its receptors plays a central role in all forms of diabetes mellitus.
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